PSD Introduction

  • Despite the success of ART, HIV persists in reservoirs and viremia rebounds if treatment is interrupted. To facilitate understanding of the genetic structure and dynamics of the HIV reservoir, we developed a public database Proviral Sequence Database (PSD) for the storage and meta-analyses of near full-length (NFL) HIV genomic RNA and proviral sequences that persist in donors on ART or that rebound after ART is interrupted.
  • PSD is a relational database containing information about host characters, treatment, HIV sequences and the sequences annotations/features. It is sponsored by the HIV Dynamics and Replication Program (HIV DRP), National Cancer Institute, NIH. The HIV DRP is a multidisciplinary research program focusing on various aspects of HIV studies.
  • Users do not need to log in to access this database.

If you have any questions, or if we miss any recent publications about HIV1 NFL provirus sequences, please contact Dr. Wei Shao at